:root {
  --bg: #f4f7fb;
  --panel: rgba(255, 255, 255, 0.97);
  --panel-border: rgba(71, 85, 105, 0.14);
  --ink: #0f172a;
  --muted: #64748b;
  --accent: #1d4ed8;
  --accent-2: #059669;
  --log-bg: #111827;
  --log-ink: #e5eefc;
  --shadow: 0 18px 44px rgba(15, 23, 42, 0.08);
}

* {
  box-sizing: border-box;
}

body {
  margin: 0;
  font-family: "Avenir Next", "Segoe UI", sans-serif;
  color: var(--ink);
  background:
    radial-gradient(circle at top left, rgba(29, 78, 216, 0.1), transparent 26%),
    radial-gradient(circle at top right, rgba(5, 150, 105, 0.08), transparent 22%),
    var(--bg);
}

.shell {
  max-width: 1440px;
  margin: 0 auto;
  padding: 28px;
}

.hero {
  display: flex;
  justify-content: space-between;
  align-items: flex-start;
  gap: 24px;
  margin-bottom: 24px;
}

.hero-copy {
  flex: 1 1 auto;
  min-width: 0;
}

.hero-brand {
  display: flex;
  align-items: center;
}

.eyebrow {
  margin: 0 0 8px;
  text-transform: uppercase;
  letter-spacing: 0.16em;
  font-size: 0.74rem;
  color: #2563eb;
}

.hero h1 {
  margin: 0;
  font-size: 2.4rem;
  line-height: 1;
}

.lede {
  max-width: none;
  margin: 14px 0 0;
  color: var(--muted);
  line-height: 1.5;
}

.hero-links {
  display: flex;
  gap: 10px;
  flex-wrap: wrap;
  justify-content: flex-end;
}

.docs-link {
  display: inline-flex;
  align-items: center;
  padding: 10px 14px;
  border-radius: 999px;
  background: #0f172a;
  color: #fff;
  text-decoration: none;
  box-shadow: 0 10px 24px rgba(15, 23, 42, 0.12);
}

.grid,
.plots {
  display: grid;
  gap: 18px;
}

.grid {
  grid-template-columns: repeat(4, minmax(0, 1fr));
  align-items: start;
}

.grid > .panel {
  height: 660px;
  display: flex;
  flex-direction: column;
  overflow: hidden;
}

.grid > .panel.hidden {
  display: none;
}

.plots {
  grid-template-columns: repeat(2, minmax(0, 1fr));
  margin-top: 18px;
}

.differential-plots {
  grid-template-columns: minmax(0, 3fr) minmax(320px, 1fr);
  align-items: stretch;
}

.panel {
  background: var(--panel);
  border: 1px solid var(--panel-border);
  border-radius: 18px;
  box-shadow: var(--shadow);
  padding: 18px;
  backdrop-filter: blur(8px);
}

#upload-panel {
}

#reference-preview-panel {
  grid-column: span 3;
  min-height: 0;
  padding: 8px;
}

#job-form {
  display: flex;
  flex: 1 1 auto;
  flex-direction: column;
  min-height: 0;
}

#qc-panel,
#qc-live-panel,
#results-panel,
#differential-panel {
  min-height: 0;
}

#qc-form,
#results-form,
#differential-form {
  display: flex;
  flex-direction: column;
  min-height: 0;
}

.panel h2 {
  margin: 0 0 14px;
  font-size: 1.02rem;
  text-transform: uppercase;
  letter-spacing: 0.06em;
}

.panel-copy {
  margin: 0 0 14px;
  color: var(--muted);
  line-height: 1.5;
  font-size: 0.92rem;
}

.panel-head {
  display: flex;
  justify-content: space-between;
  align-items: center;
  gap: 12px;
  margin-bottom: 14px;
}

.panel-head h2 {
  margin: 0;
}

.panel-head-actions {
  display: flex;
  align-items: center;
  justify-content: flex-end;
  gap: 10px;
  flex-wrap: wrap;
}

.differential-head-actions {
  display: flex;
  flex-direction: column;
  align-items: flex-end;
  gap: 10px;
}

.differential-head-row {
  display: flex;
  align-items: center;
  justify-content: flex-end;
  gap: 10px;
  flex-wrap: nowrap;
}

.differential-head-download-row {
  width: 100%;
}

.field {
  display: grid;
  gap: 6px;
  margin-bottom: 14px;
}

.field span {
  font-size: 0.82rem;
  font-weight: 700;
  color: var(--muted);
}

.field-group-label {
  font-size: 0.82rem;
  font-weight: 700;
  color: var(--muted);
}

.differential-group-label {
  font-size: 0.72rem;
  line-height: 1;
  letter-spacing: 0;
  white-space: nowrap;
}

.field-row {
  display: flex;
  justify-content: space-between;
  align-items: center;
}

input,
select {
  width: 100%;
  padding: 10px 12px;
  border: 1px solid rgba(100, 116, 139, 0.22);
  border-radius: 12px;
  background: #ffffff;
  color: var(--ink);
  box-shadow: inset 0 1px 2px rgba(15, 23, 42, 0.03);
}

select[multiple] {
  min-height: 156px;
}

#differential-group1,
#differential-group2 {
  min-height: 104px;
  max-height: 104px;
  overflow-y: auto;
}

input:focus,
select:focus {
  outline: none;
  border-color: rgba(29, 78, 216, 0.65);
  box-shadow: 0 0 0 3px rgba(29, 78, 216, 0.12);
}

input:disabled,
select:disabled {
  background: rgba(226, 232, 240, 0.75);
  color: rgba(100, 116, 139, 0.95);
  cursor: not-allowed;
}

.sample-row {
  padding: 12px;
  border-radius: 14px;
  border: 1px dashed rgba(29, 78, 216, 0.28);
  background: rgba(255, 255, 255, 0.7);
  margin-bottom: 10px;
}

.sample-field {
  display: flex;
  flex: 1 1 auto;
  flex-direction: column;
  min-height: 0;
}

#sample-container {
  flex: 1 1 auto;
  min-height: 0;
  max-height: 280px;
  overflow-y: auto;
  padding: 10px;
  padding-right: 8px;
  overscroll-behavior: contain;
  scrollbar-gutter: stable;
  border: 1px solid rgba(148, 163, 184, 0.28);
  border-radius: 16px;
  background: rgba(248, 250, 252, 0.88);
}

#job-form > .primary-btn {
  margin-top: auto;
}

.progress-shell {
  margin-top: 16px;
  flex: 0 0 auto;
}

.log-view {
  flex: 1 1 auto;
  min-height: 0;
}

.sample-actions {
  display: flex;
  justify-content: flex-end;
}

.primary-btn,
.secondary-btn,
.ghost-btn,
.download-btn {
  border: 0;
  border-radius: 12px;
  padding: 11px 14px;
  font-weight: 700;
  cursor: pointer;
  text-decoration: none;
  text-align: center;
}

.primary-btn {
  background: linear-gradient(135deg, #1d4ed8, #0f766e);
  color: #fff;
  box-shadow: 0 10px 20px rgba(29, 78, 216, 0.18);
}

.secondary-btn {
  background: rgba(59, 130, 246, 0.08);
  color: var(--ink);
}

.ghost-btn {
  background: rgba(255, 255, 255, 0.86);
  color: #0f766e;
  border: 1px solid rgba(5, 150, 105, 0.22);
  padding: 6px 10px;
}

.stack {
  display: grid;
  gap: 10px;
}

.two-col {
  display: grid;
  grid-template-columns: repeat(2, minmax(0, 1fr));
  gap: 10px;
}

.display-filter-grid {
  display: grid;
  grid-template-columns: minmax(0, 0.8fr) minmax(0, 1.2fr);
  gap: 10px;
}

.compact-field {
  margin-bottom: 0;
}

#viz1-filter1-values,
#viz1-filter2-values,
#viz2-filter1-values,
#viz2-filter2-values {
  min-height: 0;
  max-height: none;
}

.notice {
  margin-top: 12px;
  padding: 10px 12px;
  border-radius: 12px;
  background: rgba(29, 78, 216, 0.08);
  color: #1d4ed8;
}

#upload-job-id-display {
  font-size: 0.8rem;
  line-height: 1.35;
  overflow-wrap: anywhere;
  word-break: break-word;
}

.hidden {
  display: none;
}

.progress-track {
  height: 12px;
  border-radius: 999px;
  background: rgba(100, 116, 139, 0.12);
  overflow: hidden;
}

.progress-fill {
  width: 0%;
  height: 100%;
  background: linear-gradient(90deg, #0f766e, #2563eb);
  transition: width 0.25s ease;
}

.progress-label {
  margin-top: 6px;
  font-size: 0.85rem;
  color: var(--muted);
}

.log-view {
  margin: 14px 0 0;
  min-height: 96px;
  padding: 12px;
  border-radius: 14px;
  background: var(--log-bg);
  color: var(--log-ink);
  overflow-y: auto;
  font-size: 0.8rem;
}

#job-log {
  flex: 0 0 120px;
  max-height: 120px;
}

.downloads {
  display: grid;
  gap: 10px;
  margin-top: 14px;
}

#differential-archive-link,
#differential-log-link {
  margin-top: 8px;
}

.download-btn {
  background: rgba(29, 78, 216, 0.08);
  color: #1e40af;
}

.plot-area {
  min-height: 420px;
  flex: 1 1 auto;
  min-width: 0;
}

.morpheus-frame {
  width: 100%;
  min-height: 640px;
  height: 100%;
  border: 0;
  border-radius: 14px;
  background: #fff;
}

.plot-caption {
  min-height: 18px;
  margin-top: 6px;
  font-size: 0.8rem;
  color: var(--muted);
}

#reference-preview-plot {
  min-height: 100%;
}

.static-plot-shell {
  min-height: 420px;
  border-radius: 16px;
  background: rgba(255, 255, 255, 0.82);
  border: 1px solid rgba(148, 163, 184, 0.24);
  display: flex;
  align-items: center;
  justify-content: center;
  overflow: auto;
}

.static-plot {
  display: block;
  width: 100%;
  height: auto;
}

.interactive-plot-shell {
  min-height: 640px;
  max-height: 760px;
  border-radius: 16px;
  background: rgba(255, 255, 255, 0.82);
  border: 1px solid rgba(148, 163, 184, 0.24);
  overflow: auto;
  position: relative;
}

.interactive-plot-area {
  min-height: 640px;
  width: 100%;
}

.differential-primary-panel,
.differential-secondary-panel {
  display: flex;
  flex-direction: column;
  min-height: 0;
}

.differential-secondary-panel .panel-head {
  align-items: flex-start;
}

.selected-gene-label {
  color: var(--muted);
  font-size: 0.9rem;
  font-weight: 600;
  text-align: right;
}

.gene-detail-shell {
  min-height: 420px;
  max-height: 560px;
}

#differential-gene-plot {
  min-height: 420px;
}

.gene-stats {
  margin-top: 14px;
  padding: 14px;
  border-radius: 14px;
  background: rgba(241, 245, 249, 0.82);
  color: var(--ink);
  display: grid;
  gap: 8px;
}

.gene-stat-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
}

.gene-stat {
  border-radius: 12px;
  background: rgba(255, 255, 255, 0.92);
  padding: 10px 12px;
}

.gene-stat-label {
  color: var(--muted);
  font-size: 0.75rem;
  font-weight: 700;
  text-transform: uppercase;
  letter-spacing: 0.04em;
}

.gene-stat-value {
  margin-top: 4px;
  font-size: 1rem;
  font-weight: 700;
}

.empty-state {
  padding: 32px;
  color: var(--muted);
  text-align: center;
  line-height: 1.5;
}

.compact-select {
  max-width: 220px;
}

#differential-result-population {
  min-width: 280px;
}

@media (max-width: 1100px) {
  .grid,
  .plots {
    grid-template-columns: 1fr;
  }

  .hero {
    flex-direction: column;
  }

  .hero-brand {
    align-items: flex-start;
  }

  .grid > .panel {
    height: auto;
    overflow: visible;
  }

  #upload-panel {
    height: auto;
  }

  #reference-preview-panel {
    grid-column: auto;
    height: auto;
  }

  #sample-container {
    max-height: 360px;
  }
}

@media (max-width: 700px) {
  .shell {
    padding: 18px;
  }

  .two-col {
    grid-template-columns: 1fr;
  }

  .gene-stat-grid {
    grid-template-columns: 1fr;
  }
}

.compact-shell {
  min-height: 100vh;
  padding: 18px 18px 16px;
  display: flex;
  flex-direction: column;
  gap: 14px;
}

.compact-hero {
  max-width: 100%;
  margin: 0;
  align-items: center;
  gap: 16px;
  position: relative;
  display: flex;
  justify-content: space-between;
}

.compact-hero .hero-copy {
  min-width: 0;
}

.compact-hero h1 {
  font-size: 2.4rem;
}

.sandbox-main {
  flex: 1 1 auto;
  min-height: 0;
  display: block;
}

.sandbox-run-grid {
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 16px;
}

.sandbox-run-grid.preupload-mode {
  grid-template-columns: minmax(0, 1fr) minmax(0, 2fr);
}

.sandbox-run-grid > .panel {
  height: 660px;
  min-height: 0;
  overflow: hidden;
}

.sandbox-run-grid.preupload-mode #qc-panel {
  display: none !important;
}

.sandbox-run-grid.preupload-mode #qc-live-panel {
  display: none !important;
}

.sandbox-run-grid.preupload-mode #reference-preview-panel {
  grid-column: 2;
}

.sandbox-run-grid.workflow-mode #reference-preview-panel {
  display: none;
}

.sandbox-preview-panel {
  min-height: 0;
  height: 660px;
  padding: 8px;
}

.sandbox-preview-panel.hidden {
  display: none;
}

#qc-live-panel {
  min-height: 0;
}

#qc-live-plot {
  min-height: 320px;
}

#qc-live-caption {
  min-height: 36px;
  margin-top: 8px;
}

#ambient-live-plot {
  min-height: 180px;
  margin-top: 10px;
}

#ambient-live-caption {
  min-height: 24px;
  margin-top: 8px;
}

.ambient-plot-area {
  flex: 0 0 auto;
}

.workspace-tabs {
  display: flex;
  align-items: center;
  gap: 8px;
  flex-wrap: wrap;
}

.hero-centered-tabs {
  position: absolute;
  left: 50%;
  transform: translateX(-50%);
}

.hero-links {
  margin-left: auto;
}

.workspace-tab-btn {
  border: 1px solid rgba(148, 163, 184, 0.22);
  background: rgba(255, 255, 255, 0.78);
  color: var(--muted);
  border-radius: 999px;
  padding: 9px 14px;
  font-weight: 700;
  cursor: pointer;
}

.workspace-tab-btn.active {
  background: linear-gradient(135deg, rgba(29, 78, 216, 0.12), rgba(15, 118, 110, 0.12));
  color: var(--ink);
  border-color: rgba(29, 78, 216, 0.28);
  box-shadow: 0 12px 24px rgba(29, 78, 216, 0.08);
}

.workspace-panel {
  display: none;
  min-height: 0;
}

.workspace-panel.active {
  display: block;
  min-height: 0;
}

.explore-workspace {
  min-height: 0;
  display: grid;
  grid-template-columns: 340px minmax(0, 1fr);
  gap: 16px;
}

.explore-controls-panel,
.explore-results-column,
.differential-controls-panel,
.differential-results-column {
  min-height: 0;
}

.explore-controls-panel {
  display: flex;
  flex-direction: column;
  overflow: auto;
}

.explore-controls-panel.hidden {
  display: none;
}

.explore-controls-panel #results-form {
  display: flex;
  flex-direction: column;
  min-height: 0;
}

.panel-head-stack {
  display: flex;
  align-items: center;
  gap: 10px;
  flex-wrap: wrap;
  min-width: 0;
}

.panel-head-column {
  display: flex;
  flex-direction: column;
  align-items: stretch;
  gap: 12px;
}

.panel-head-topline {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 12px;
}

.panel-head-stack h2 {
  margin: 0;
}

.expression-head-stack {
  flex: 1 1 auto;
}

.expression-head-stack #gene-query {
  max-width: 240px;
}

.viz-controls-grid {
  display: grid;
  grid-template-columns: repeat(3, minmax(0, 1fr));
  gap: 10px;
}

.viz-controls-grid .inline-field {
  min-width: 0;
}

.viz-filter-stack {
  gap: 8px;
}

.inline-field {
  display: flex;
  flex-direction: column;
  gap: 4px;
  margin: 0;
  min-width: 180px;
}

.inline-field.hidden {
  display: none;
}

.compact-inline-field {
  min-width: 190px;
}

.inline-field span {
  font-size: 0.72rem;
}

.explore-results-column {
  min-width: 0;
  display: flex;
  flex-direction: column;
  min-height: 0;
}

.differential-workspace {
  min-height: 0;
  display: grid;
  grid-template-columns: 340px minmax(0, 1fr);
  gap: 16px;
  align-items: stretch;
}

.differential-controls-panel {
  display: flex;
  flex-direction: column;
  overflow: auto;
  min-height: 860px;
}

.differential-controls-panel.hidden {
  display: none;
}

.differential-results-column {
  min-width: 0;
  display: flex;
  flex-direction: column;
  min-height: 0;
}

.explorer-empty {
  min-height: 560px;
  border-radius: 18px;
  border: 1px dashed rgba(148, 163, 184, 0.35);
  background: rgba(255, 255, 255, 0.65);
  display: flex;
  align-items: center;
  justify-content: center;
  font-size: 1rem;
}

.explorer-empty.hidden {
  display: none;
}

.plots {
  margin-top: 0;
}

#baseline-results-view.hidden,
#differential-results-view.hidden {
  display: none;
}

#baseline-results-view {
  min-height: 560px;
  grid-template-columns: repeat(2, minmax(0, 1fr));
}

#differential-results-view {
  min-height: 860px;
}

#reference-preview-plot {
  min-height: 100%;
}

#baseline-results-view > .panel,
#differential-results-view > .panel {
  min-height: 0;
  overflow: hidden;
  display: flex;
  flex-direction: column;
}

#upload-panel,
#qc-panel {
  min-height: 0;
  display: flex;
  flex-direction: column;
  overflow: hidden;
}

#qc-form .primary-btn {
  margin-top: 8px;
  margin-bottom: 10px;
  position: relative;
  z-index: 1;
}

#qc-panel > .progress-shell {
  margin-top: 0;
}

#qc-cell-status {
  flex: 0 0 auto;
  min-height: 56px;
  line-height: 1.3;
}

#sample-container {
  max-height: 280px;
}

#job-log {
  flex: 0 0 180px;
  min-height: 180px;
  max-height: 180px;
  overflow-y: auto;
  overflow-x: auto;
  white-space: pre;
}

.download-btn {
  padding: 14px 16px;
  font-size: 0.92rem;
}

@media (max-width: 1500px) {
  .sandbox-run-grid {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .explore-workspace,
  .differential-workspace {
    grid-template-columns: 300px minmax(0, 1fr);
  }
}

@media (max-width: 1180px) {
  .compact-shell {
    height: auto;
  }

  .compact-hero {
    position: static;
    flex-direction: column;
    align-items: flex-start;
  }

  .sandbox-run-grid,
  .explore-workspace,
  .differential-workspace,
  #baseline-results-view,
  .differential-plots {
    grid-template-columns: 1fr;
  }

  .sandbox-run-grid.preupload-mode #reference-preview-panel {
    grid-column: auto;
  }

  .sandbox-run-grid > .panel,
  .sandbox-preview-panel,
  #reference-preview-panel {
    height: auto;
  }

  .hero-centered-tabs,
  .hero-links {
    position: static;
    transform: none;
    margin-left: 0;
  }
}